New Plant Engineering Method Promises to Dramatically Improve Biofuel and Bioproduct Development

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Young Arabidopsis plants from the same transformation experiment expressing a red reporter pigment, demonstrating the variability that can occur in transformation outcomes. Increasing the efficiency of transformation and control over outcomes can greatly help real-world plant biotechnology applications. Photo: Matthew Szarzanowicz
Young Arabidopsis plants from the same transformation experiment expressing a red reporter pigment, demonstrating the variability that can occur in transformation outcomes. Increasing the efficiency of transformation and control over outcomes can greatly help real-world plant biotechnology applications (photo by Matthew Szarzanowicz).

December 10, 2024 | Originally published by Lawrence Berkeley National Laboratory (LBL) on November 7, 2024

The ability to genetically engineer plants is largely thanks to a microscopic helper:  a bacterium called Agrobacterium tumefaciens. Agrobacterium in the wild causes damaging tumors in flowering plants, including some economically important crops, but its ability to insert its own DNA into host plants is what makes it both a pest to farmers and a powerful tool for biotechnology.

New research by a team that includes scientists from Lawrence Berkeley National Laboratory (Berkeley Lab) shows that some simple changes to Agrobacterium can significantly improve the efficiency of introducing DNA into a genome, also known as “transformation.” The work opens up new opportunities to more efficiently optimize crop plants and fungi for conversion into biofuels and bioproducts.

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